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Klonopin is useful as an adjunct treatment of petit mal varian both akinetic and myolonic seizures. Clonazepam may also be used to patients who have absence seizures and have failed to react to succinimide.
Clonazepam cannot be used for patients with a history of sensitive of benzodiazepines nor in patients with significant liver disease. Patient with open angle glaucoma can receive this treatment but not with acute narrow angle glaucoma.
Patients taking this drug are cautioned in engaging in hazardous occupations that require mental alertness such as driving a vehicle or operating a machine. They are also warned of alcohol intake or other depressant drugs while on Klonopin therapy.
Klonopin, like other antiepileptic drugs, increases the risk of suicidal tendencies. Patients taking this drug are closely monitored if they show any signs of suicidal thoughts, unusual mood changes, worsening of depression.
Perinatal conditions were reported in children born from a mother taking Clonazepam during the last quarter of pregnancy. Nursing mothers should not take Klonopin.
Klonopin may also increase or precipitate the incidence of the onset of generalized of tonoic-clonic seizures or grand mal requiring the addition of appropriate anticonvulsants or an increase in the dosage.
Treatment involves monitoring of respiration, blood pressure, pulse, general supportive measures and gastric lavage. IV should be administered and adequate airway ,maintained.
Clonazepam is available as an oral disintegrating tablet which makes it easy to use. Upon opening the pouch, peel back the foil on the blister. Do not push tablet through foil and immediately upon opening the blister, with dry hand, remove the tablet and place it inside the mouth. The tablet will disintegrate rapidly in the saliva so you can swallow it even without water. An initial dose of 0.25 mg/day is given for adults and gradually increased to 1 mg after 3 days.